Ronghu Wu

Georgia Institute of Technology（Professor）

Dr. Ronghu Wu is a professor in the School of Chemistry and Biochemistry at Georgia Institute of Technology. His group has worked on the development of mass spectrometry-based methods for global analysis of protein modifications, especially glycosylation, and applying them for biomedical research. Glycosylation is one of the most common and important protein modifications in mammalian cells, and it regulates nearly every extracellular activity. Aberrant protein glycosylation is directly related to human diseases including cancer and infectious diseases. Global analysis of protein glycosylation will advance our understanding of protein functions, cellular activities, and disease mechanisms, leading to the identification of glycoproteins as effective biomarkers and drug targets. However, it is very challenging to globally analyze glycoproteins in complex biological samples because of the heterogeneity of glycans and the low abundance of many glycoproteins. It is urgently needed to develop effective methods to comprehensively characterize protein glycosylation. He is a recipient of Georgia Tech (GT) Blanchard Assistant Professorship (2014), NSF CAREER Award (2015), American Society for Mass Spectrometry Research Award (2016), GT College of Sciences Cullen-Peck Faculty Scholar Award (2019), and GT Vasser-Woolley Professorship in 2021.